What Happened?
Cambridge, MA-based Generation Bio Appointed Sara Den Besten as Head of Human Resources
Date of management change: May 08, 2018
Cambridge, MA-based Generation Bio Appointed Sara Den Besten as Head of Human Resources
Generation Bio is innovating genetic medicines to provide durable, redosable treatments for people living with rare and prevalent diseases. The company`s non-viral platform incorporates a novel DNA construct called closed-ended DNA, or ceDNA; a unique cell-targeted lipid nanoparticle delivery system, or ctLNP; and a highly scalable capsid-free manufacturing process that uses its proprietary cell-free rapid enzymatic synthesis, or RES, to produce ceDNA. The platform is designed to enable multi-year durability from a single dose, to deliver large genetic payloads, including multiple genes, to specific tissues, and to allow titration and redosing to adjust or extend expression levels in each patient. RES has the potential to expand Generation Bio`s manufacturing scale to hundreds of millions of doses to support their mission to extend the reach of genetic medicine to more people, living with more diseases, around the world.
Sara Den Besten is Head of Human Resources at Generation Bio. Previously, Sara held various senior HR leadership roles in the industry.
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